A Sunday Business Post story in Ireland cites sources claiming the social media platform and its parent company ByteDance will use the campus as a primary European data centre.
The campus is set to open by the end of this year, and TikTok is expected to spend around $500 million on its deployment at the site.
The Clondalkin Industrial Estate in total supports up to 84MW of power across around 480,000 sq ft of data centre space. The company was recently granted planning permission to build another facility in County Wicklow, Ireland, which will offer 100MW.
Chinese firm ByteDance says all its data is currently stored and managed in data centres in the US and Singapore.
But previous US president Trump claimed the company posed a national security threat as the administration believed it was sending data back to China.
At one point the company was being forced by Trump to sell-off its US operations, with Walmart and Oracle nearing a purchase.
ByteDance fought the sale in the US courts and by the time Trump lost the election to president Biden, a forced spin-off was taken off the table.